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Welcome to Novartis Oncology - The Global Site for Novartis Oncology

 

 

 

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Global Cancer Crisis

Cancer knows no borders. Virtually no country, no community, and hardly a family, is untouched by cancer. Cancer is a tremendous burden on patients, families and humanity.

Novartis Oncology aims to raise awareness and create understanding of cancer care in underserved communities.

Global Cancer Statistics
Cancer in the Developing World
Inequitable Distribution of Global Health Workforce
Cancer in Africa
Situation in Kenya

Global Cancer Statistics

According to the World Health Organization (WHO) and the International Atomic Energy Agency (IAEA) the world is facing a health crisis called—cancer.

  • Every year, at least 7 million people die from cancer, more than
    HIV/AIDS, malaria, and tuberculosis combined.[1]
  • By 2020, the number of new cases each year could rise to 16 million, killing 10.3 million people per year worldwide.[2],[3]
  • By 2020, developing countries are predicted to account for 70% of new cases of cancer every year.[4]
  • By 2030, there will be 27 million new cases, 17 million cancer deaths per year, and 75 million persons alive with cancer.[5]

Cancer in the Developing World

  • Cancer is often regarded as a disease of the developed world, but incidence in low- and middle-income countries is on the rise,[5] and three quarters of all annual cancer deaths occur in low- and middle-income countries.[1]
  • The high prevalence of cancer is shifting from developed nations to poorer, less medically-equipped countries and their underserved communities.[1]
  • In many of these low- and middle-income countries, the priority of cancer is so low that no resources are available for cancer prevention and diagnosis, and cancer treatment facilities are not universally available.[3]
  • Cancer has a lower incidence in the low- and middle-income countries, yet survival rates are much lower, largely because of delays in diagnosis leading to the patient presenting with advanced disease.[6]
  • More developed regions have lower cancer mortality despite having a higher cancer incidence. Conversely, some less developed regions have a relatively high cancer mortality despite having low cancer incidence.[7]
  • The mortality-to-incidence ratio varies widely across geographic regions, with the highest ratio in Africa.[7]

2002 Worldwide Age-Standardized Incidence, Mortality,
and Mortality-to-Incidence Ratios[8]

 

Males

Females

All cancer sites, except skin.

Incidence

Mortality

Mortality-
to-
Incidence Ratio*

Incidence

Mortality

Mortality-
to-
Incidence Ratio*

World

5,802,531

 

3,796,383

 

0.66

 

5,061,968

 

2,928,548

 

0.57

More developed

2,698,175

1,503,060

0.54

2,317,939

1,185,412

0.45

Less developed

3,092,817

2,284,779

0.75

2,736,696

1,738,455

0.65

Continent

 

 

 

 

 

 

North America

834,546

331,226

0.38

735,974

300,745

0.37

Oceania

56,119

24,812

0.43

47,606

19,611

0.37

Europe

1,499,642

958,248

0.62

1,321,129

743,224

0.49

Central/South America

365,497

221,243

0.62

401,078

215,395

0.54

Asia

2,697,813

1,983,473

0.74

2,181,139

1,372,455

0.63

Africa

311,363

251,099

0.83

338,397

255,013

0.77


* As an indirect measure of cancer survival, a mortality-to-incidence ratio is calculated by dividing the mortality rate by the incidence rate; mortality-to-incidence approaching 1.0 suggests a limited survival.


Inequitable Distribution of Global Health Workforce

Pressing health needs across the globe cannot be met without adequate numbers of well-trained healthcare professionals available.[9]

Fifty-seven countries, most of them in Africa and Asia, face a severe health workforce crisis. The World Health Organization (WHO) estimates that at least 4,250,000 health workers are needed to fill the gap.[9]


Health Workforce in
Sub-Saharan Africa vs. the Americas [9]

Sub-Saharan Africa†

The Americas‡

11% of the world's population

14% of the world's population

25% of the global burden of disease

10% of the global burden of disease

3% of the world's health workers

42% of the world's health workers

<1% of global health expenditure

>50% of global health expenditure


    † African Region: Algeria, Burkina Faso, Cameroon, Ethiopia, Guinea, Kenya, Malawi, Mauritius, Mozambique, Namibia, Niger, Nigeria, Rwanda, Senegal, South Africa, Togo, Uganda, United Republic of Tanzania, Zambia, Zimbabwe.

    ‡ Region of the Americas: Argentina, Bahamas, Bolivia, Brazil, Canada, Chile, Columbia, Costa Rica, Ecuador, El Salvador, Guatemala, Honduras, Mexico, Nicaragua, Panama, Paraguay, Peru, Suriname, Trinidad and Tobago, United States of America, Uruguay.

Cancer In Africa

Africa is an extraordinarily diverse continent. Approximately 830 million people populate Africa's 53 countries. Cancer is an increasingly public health problem in Africa.[10]

Cancer treatment is unavailable in many regions for the 650,000 Africans who develop cancer annually, resulting in about 510,000 deaths—almost 80% of all cancer cases in Africa.[10]

By 2020 Africa will account for more than one million new cancer cases a year, and they are the least able of all developing countries to cope, having few cancer care services. Lack of resources and basic infrastructure means that most Africans have no access to cancer screening, early diagnosis, treatment or palliative care.[4]

According to the Africa-Oxford Cancer Consortium (AfrOx):[4]

  • In Africa, cancer is a sentence to a painful and distressing death.
  • Life-saving radiation treatment is available in only 21 of Africa's
    53 countries, or to less than 20% of the total population.

Situation in Kenya

The Republic of Kenya, in eastern Africa, borders the Indian Ocean, between Somalia and Tanzania. Kenya is well known for its scenic landscapes and vast wildlife preserves. Kenya's Indian Ocean border has some of the finest beaches in Africa. Inland are densely inhabited highlands renowned for both their tea plantations and their variety of animal species. Kenya's western provinces, marked by lakes and rivers, are forested, while a small portion of the north is desert and semi desert. The country's varied and unique wildlife and picturesque geography have historically drawn European and North American visitors, and tourism has been an important contributor to Kenya's economy.[11]

Kenya (slightly more than twice the size of Nevada) has a population of nearly 37 million. The capital city of Nairobi has a population of about 3 million.[6], [12]

In Kenya, cancer ranks third as a cause of death after infections (including HIV) and cardiovascular diseases. In 2005, cancer killed approximately 18,000 people in Kenya. More than 60% of those people were under the age of 70 years.[13]

Life expectancy at birth in Kenya (55 years) is certainly affected by the country's AIDS pandemic and that 50% of the population is living below the poverty line. [12]

Like other African nations, Kenya's AIDS pandemic severely strains healthcare resources.[6]

Despite the fact that cancer ranks third as a cause of death after infections (including HIV) and cardiovascular diseases, cancer is not on the Ministry of Health's list of priorities.[6]

Kenyatta National Hospital in Nairobi is the country's chief referral and teaching institution. There are also provincial and district hospitals. In rural areas, health centers and dispensaries offer diagnostic services, obstetric care, and outpatient treatment, although they often lack adequate facilities, trained personnel, and medications.[11]

While the fight against cancer is secondary to other important public health priorities, change and advancement are noticeable:[6]

  • Training in cancer management and care is conducted at the University of Nairobi at the post-graduate level in medicine, surgery, hematology and pathology.
  • Kenyatta National Hospital offers specialized services relevant to cancer: radiotherapy, medical oncology and hematology, surgical oncology, pathology and palliative care.
  • Kenyan physicians are joining with non-governmental organizations (NGOs) to help raise awareness of cancer, and are working toward prevention, early detection, diagnosis and treatment.
References
[1]    World Health Organization publication: The World Health Organization's Fight Against Cancer: Strategies that Prevent, Cure and Care; Geneva, Switzerland: WHO Press, 2007. Access March 27, 2008. http://www.who.int/cancer/publications/en/index.html.
[2]    World Health Organization and International Union Against Cancer publication: Global Action Against Cancer NOW! Updated Edition 2005; Geneva, Switzerland: WHO Press.
[3]    International Union Against Cancer (UICC) website. Accessed March 30, 2008. www.uicc.org.
[4]    Africa-Oxford Cancer Consortium (AfrOx) website, University of Oxford. Accessed March 31, 2008. www.afrox.org.
[5]    Boyle P. The Globalisation of Cancer. Lancet 2006; 368: 629-630.
[6]    International Network for Cancer Treatment and Research (INCTR) website. Accessed March 25, 2008. www.inctr.org/publications/2007.
[7]    Ma X and Yu H. Global Burden of Cancer. Yale Journal of Biology and Medicine 2006; 79: 85-94.
[8]    Kamangar F, et al. Patterns of Cancer Incidence, Mortality, and Prevalence Across Five Continents: Defining Priorities to Reduce Cancer Disparities in Different Geographic Regions of the World. Journal of Clinical Oncology 2006; Vol 24, No 14: 2137-2150.
[9]    World Health Organization (WHO) website. Accessed March 27, 2008. www.who.int/mediacentre/factsheets/en/.
[10]    Cancer Control Planning and Implementation: A View from Tanzania. Presentation delivered by Dr. Twalib Ngoma, at the London Meeting: Cancer Control in Africa; May 10-11, 2007. Presentation downloaded from Africa-Oxford Cancer Consortium (AfrOx) website, University of Oxford. Accessed March 31, 2008. www.afrox.org/london/presentations.
[11]    Kenya (2008). In Encyclopedia Britannica. Accessed March 27, 2008 from Encyclopedia Britannica Online: www.britannica.com/bps/topic/315078/Kenya.
[12]    The Central Intelligence Agency: The World Fact Book website. Accessed on March 20 and March 27, 2008. www.cia.gov/library/publications/the-world-factbook/.
[13]    World Health Organization (WHO) website. Accessed March 27, 2008. www.who.int/infobase/report.
 
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